张玮莹助理研究员
联系电话：027-84223798转208
Email：zwy2428@163.com
教育背景
●2010.9 ~ 2014.6 华中师范大学生命科学院农药学博士
●2011.10~ 2013.10 美国西北太平洋国家实验室 联合培养博士
●2007.9 ~ 2010.7华中师范大学生命科学院细胞生物学硕士
●2001.9 ~ 2005.7华中师范大学生命科学院生物技术专业学士
工作经历
●2014.6-至今江汉大学交叉学科研究院助理研究员
●2015.7-10日本京都大学访问学者
研究领域
●基于微流控芯片的肿瘤生物检测分析研究
●诱导多能干细胞的定向分化及再生医学研究
科研项目
●国家自然科学基金青年项目，31600801，一种基于微柱和纳米纤维的3D微流控芯片构建及其在循环肿瘤细胞捕获与释放上的应用研究，2017/01 - 2019/12，20万元，在研，主持
●国家自然科学基金重大研究计划培育项目，91539107，利用微流控芯片技术研究AcSDKP对血管损伤后的重塑作用与机制，2016/01 - 2018/12，89.2万元，在研，参加
●武汉市科技局应用基础研究计划项目，2015011701011595，基于微流控芯片的肿瘤细胞与肿瘤分子联合诊断新方法研究，2015/12 - 2017/12，15万元，已结题，主持
●湖北省自然科学基金青年项目，2015CFB610，循环肿瘤细胞俘获及相关标志物的微流控芯片多通道检测，2015/04 - 2016/12，5万元，已结题，主持
已发表文章(SCI)
22. C. Cai, Z. Guo, Y. Cao*, W. Zhang*, Y. Chen, A dual biomarker detection platform for quantitating circulating tumor DNA (ctDNA), Nanotheranostics, 2018, 2,12-20.
21. Z. Zheng, H. Ye, J. Wang, T. Zhang, Q. You, H. Li, R. He, Y. Chen, W. Zhang*, Y. Cao*, Visible-light-controllable drug release from multilayer-coated microneedles, J. Mater. Chem. B, 2017, 5, 7014-7017.
20. W. Zhang*, Z. Guo*, Y. Chen, Y. Cao*, Nanomaterial based biosensors for detection of biomarkers of exposure to OP pesticides and nerve agents: a review, Electroanal,2017, 29, 1206-1213.
19. H. Ye, Z. Guo, M. Peng, C. Cai, Y. Chen, Y. Cao*, W. Zhang*, Methyl parathion degrading enzyme-based nano-hybrid biosensor for enhanced methyl parathion recognition, Electroanal., 2016, 28, 1591-1596.
18. Z. Guo*, A. Florea, M. Jiang, W. Zhang, A. Zhang, R. Sandulescu, N. Jaffrezic-Renault*, Molecularly imprinted polymer/metal organic framework based chemical sensors, Coatings, 2016, 6, 42.
17. X. Cai, Y. Luo, W. Zhang, D. Du*, Y. Lin*, pH-sensitive ZnO Quantum Dots-doxorubicin nanoparticles for lung cancer targeted drug delivery, ACS Appl. Interfaces, 2016, 8, 22442-22450.
16. R. He, J. Xiao, M. Zhang, Z. Zhang, W. Zhang, Y. Cao, Y. Liu*, Y. Chen*, Artificial honeycomb-inspired TiO2 nanorod arrays with tunable nano/micro interfaces for improving poly(dimethylsiloxane) surface hydrophobicity, J. Mater. Sci., 2016, 51, 2935-2941.
15. N. Li, T. Xiao, Z. Zhang, R. He, D. Wen, Y. Cao*, W. Zhang*, Y. Chen, A 3D graphene microchips and an Au-enwrapped silica nanocomposites based supersandwich cytosensor toward capture and analysis of circulating tumor cells, Nanoscale, 2015, 7, 16354- 16360.
14. J. Wang, J. Li, N. Li, X. Guo, L. He, X. Cao, W. Zhang, R. He*, Z. Qian*, Y. Cao*, Y. Chen, A bottom-up approach to dual shape-memory effects, Chem. Mater., 2015, 27, 2439- 2448.
13. J. Xiao, W. He, Z. Zhang, W. Zhang, Y. Cao, R. He*, Y. Chen*, PDMS micropillar-based microchip for efficient cancer cell capture, RSC Adv., 2015, 5, 52161- 52166.
12 W. He, J. Xiao, Z. Zhang,W. Zhang, Y. Cao, R. He*, Y. Chen*, One‑step electroplating 3D template with gradient height to enhance micromixing in microfluidic chips, Microfluid Nanofluid, 2015, 54, 829-836.
11. W. Zhang, A.M. Asiri, D. Liu, D. Du, Y. Lin*, Nanomaterials-based biosensors for environmental and biological monitoring of organophosphorus pesticides and nerve agents, Trend Anal. Chem., 2014, 54, 1-10.
10. W. Zhang, D. Du, D. Gunaratne, R. Colby, Y. Lin*, J. Laskin*, Polyoxometalate-graphene nanocomposites modified electrode for electrocatalytic detection of ascorbic acid, Electroanal., 2014, 26, 178-183.
9. D. Gunaratne, W. Zhang,Y. Lin, J. Laskin*, Controlling the Charge State and Redox Properties of Supported Polyoxometalates via Soft Landing of Mass-Selected Ions, J. Phys. Chem. C, 2014, 118, 27611- 27622.
8. X. Ge,W. Zhang（co-first）, Y. Lin, D. Du*, Magnetic Fe3O4@TiO2 nanoparticles- based test strip immunosensing device for rapid detection of phosphorylated butyrylcholinesterase, Biosens. Bioelectron., 2013, 50, 486-491.
7. W. Zhang#, Y. Tang#, D. Du, J. Smith, C. Timchalk, D. Liu*, Y. Lin*, Direct analysis of trichloropyridinol in human saliva using an Au nanoparticles-based immunochromatographic test strip for biomonitoring of exposure to chlorpyrifos, Talanta, 2013, 114, 261-267.
6. W. Zhang#, X. Ge#, Y. Tang, D. Du, D. Liu*, Y. Lin*, Nanoparticle-based immunochromato- graphic test strip with fluorescent detector for quantification of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphorus agents, Analyst, 2013, 138, 5431-5436.
5. Y. Zhao, W. Zhang, Y. Lin, D. Du*, The vital function of Fe3O4@Au nanocomposites for hydrolase biosensor design and its application in detection of methyl parathion, Nanoscale, 2013, 5, 1121-1126.
4. L. Zhang, L. Long, W. Zhang, D. Du, Y. Lin*, Study of inhibition, reactivation and aging processes of pesticides using graphene nanosheets/gold nanoparticles-based acetylcholinesterase biosensor, Electroanal., 2012, 24, 1745 – 1750.
3. D. Du, Y. Tao, W. Zhang, D. Liu*, H. Li, Oxidative desorption of thiocholine assembled on core–shell Fe3O4/AuNPs magnetic nanocomposites for highly sensitive determination of acetylcholinesterase activity: An exposure biomarker of organophosphates, Biosens. Bioelectron., 2011, 26, 4231-4235.
2. W. Zhang, J. Ding, Y. Qin, D. Liu*, D. Du*, One-step electrochemically deposited gold nanoparticles interface grafted with avidin for acetylcholinesterase biosensor design, J. Nanosci. Nanotech., 2010, 10, 5685-5691.
1. D. Du*, W. Chen, W. Zhang, D. Liu, H. Li, Y. Lin*, Covalent coupling of organophosphorus hydrolase loaded quantum dots to carbon nanotube/Au nanocomposite for enhanced detection of methyl parathion, Biosens. Bioelectron., 2010, 25, 1370-1375.